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Benefits of CBD for animal health


The research for hemp and CBD use has been quickly evolving and we now have a growing body of evidence supporting the benefits of CBD in animals. Look below for a listing of current peer-reviewed journal articles looking at CBD safety and dosing for dogs and cats. Additionally, topics covering osteoarthritis, seizures, and even neoplasia (cancer) have been reported on with respect to CBD in canines. A case study in a horse has been published, and safety studies are expected soon with equines. Read on below for more information and remember that our VetCS team is always here to help you if you have any questions.

What's in Cannabis?

Cannabis plants produce over 180 known cannabinoids, with cannabidiol (CBD) being one of those. THC (primary psychoactive component in cannabis) is also a cannabinoid. Other documented, but less researched cannabinoids include: cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC).

All mammals have an endocannabinoid system (ECS) that is activated by substances in our bodies called endocannabinoids. Phytocannabinoids are substances like CBD that are produced by plants and function at the same receptors in the ECS. Based on the location of the receptors in the body, therapeutic targets using CBD and hemp can be employed to gain a beneficial outcome.

Research on cannabinoid therapy for animals:

VetCS has gathered helpful information on the research of cannabinoid therapy for animals. If you have a question or concern about giving your pet or horse CBD products, pleasecontact our veterinarian team.

Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs

Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs

Oral Transmucosal Cannabidiol Oil Formulation as Part of a Multimodal Analgesic Regimen: Effects on Pain Relief and Quality of Life Improvement in Dogs Affected by Spontaneous Osteoarthritis.

Treatment using Cannabidiol for mechanical allodynia in a horse

Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats.

Preliminary Investigation of the Safety of Escalating Cannabinoid Doses in Healthy Dogs

Characterization of synovial fluid endocannabinoids in dogs with osteoarthritis

The use of cannabinoids in animals and therapeutic implications for veterinary medicine; a review

The Use of Cannabidiol-Rich Hemp Oil Extract to Treat Canine Osteoarthritis-Related Pain: A Pilot Study

US veterinarians' knowledge, experience, and perception regarding the use of cannabidiol for canine medical conditions

Polyphenols and Cannabidiol Modulate Transcriptional Regulation of Th1/Th2 Inflammatory Genes Related to Canine Atopic Dermatitis

The effect of cannabidiol on canine neoplastic cell proliferation and mitogen-activated protein kinase activation during autophagy and apoptosis

Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy

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