Cannabis plants produce over 180 known cannabinoids, with cannabidiol (CBD) being one of those. THC (primary psychoactive component in cannabis) is also a cannabinoid. Other documented, but less researched cannabinoids include: cannabigerol (CBG), cannabinol (CBN), cannabichromene (CBC) and many others. CBD is a non-psychoactive compound, so your pet will not experience a "high". VetCS CBD is cultivated from Cannabis sativa strains grown local to us in Colorado.
All mammals have an endocannabinoid system (ECS) that is activated by substances in our bodies called endocannabinoids. Phytocannabinoids are substances like CBD that are produced by plants and function at the same receptors in the ECS. At this time there are two known receptors, CB1 and CB2. CB1 receptors are found in high numbers in our brain and central nervous system. CB2 receptors are found in high density in our immune systems. Other locations of CB1 and CB2 receptors include skin, liver, bone, and the gastrointestinal tract. The majority of CBD's mechanism of action is still being studied.
Two major universities, Colorado State University and Cornell University, are currently conducting clinical trials on dogs and cats. They have both published journal articles on safety and dosing (see below). The doses we have formulated for VetCS products are based off of the protocols used in these studies. Every pet is different in their tolerance and effect from CBD, so please contact us if you have questions!
What's that Smell?
What makes a lemon smell like a lemon? Terpenes! This class of compounds originate from plants and gives them their signature smell (pinene is produced by pine trees, for example). Terpenes have long been recognized for their healing properties when used as essential oils. We at VetCS take terpenes very seriously. Our custom terpene profile syngergistically improves the benefits of cannabinoid therapy. Terpenes are very sensitive to heat damage; therefore, our process is designed to preserve all the effectiveness of terpenes. Our terpenes are also sourced from the highest quality sources- we use 99% pure terpenes whereas many products are formulated using 4% formulas or less!
Watch Dr. Sanjay Gupta's video on CNN for more information, starting at 0:52 seconds.
Research on CBD and Hemp Extracts
Although controlled veterinary research on CBD and hemp extracts is limited, there are studies performed in humans and lab animal models that can help us understand CBD's application and usefulness. Project CBD is a well balanced source of information. Below are a few veterinary-specific recently published articles regarding cannabis therapy in animals: